html

<div class="container-diy">
  <div class="row-diy">
    <div class="col-diy-main"></div>
    <div class="col-diy-side"></div>
  </div>
</div>

scss

.container-diy {
  @include make-container();
  background-color: #eee;
  height: 300px;
}

.row-diy {
  @include make-row();
  height: 100%;
}

.col-diy-main {
  @include make-col(6);
  @include make-col-offset(2);
  background-color: lightblue;
  height: 50%;
  align-self: start;
}

.col-diy-side {
  @include make-col(2);
  background-color: lightsalmon;
  height: 50%;
  align-self: flex-end;
}

/wiki/wiki/bootstrap4-mixins-diy.png

https://getbootstrap.com/docs/4.1/layout/grid/#mixins